PAPER TITLE :ANTIBACTERIAL PROPERTIES OF EXTRACTS OF CORIOLOPSIS SPECIES AGAINST STAPHYLOCOCCUS AUREUS OBTAINED FROM DIFFERENT CLINICS AND LABORATORIES IN SOUTH WEST NIGERIA

FUTA JOURNAL OF RESEARCH IN SCIENCE | VOLUME 8 NUMBER 2 2012

Paper Details

  • Author(s) : V.O. Oyetayo* and K. Dauda
  • Abstract:

The antibacterial properties of ethanol (CET), ethylacetate (CEA) and petroleum ether (CPE) extracts from
the macrofungus, Coriolopsis species, on ten clinical isolates of Staphylococcus aureus was investigated.
CET and CEA inhibited the growth of Staphylococcus aureus with zones of inhibition ranging from 2 to
6mm at 100mg/ml concentration. CET showed higher antimicrobial effect (2 to 6mm) on eight of the
clinical isolates of Staphylococcus aureus. Comparatively, CEA inhibited 6 of the isolates with zones of
inhibition of 1 to 2mm while the commercial antibiotics, amoxicillin and streptomycin, used as positive
control inhibited two and three isolates respectively with inhibition zones in the range, 3 to 7mm. Total
phenolic compound in CET (0.72mg/ml) was higher than that of CEA (0.28mg/ml) and CPE (0.43mg/ml)
and this may be responsible for the better antimicrobial effect displayed by CET. CET and CEA have
potentials as source of effective antimicrobial agent against Staphylococcus aureus that had exhibited
resistance against many common commercial antibiotics.
Keywords: Antimicrobial, Coriolopsis, Extract, clinical, Staphylococcus.